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URL: | https://www.deadiversion.usdoj.gov/...nov_2018/bielawski.pdf |
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Title: | Reducing Opioid Prescribing |
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Body: | Bret Bielawski, DO FACP
Reducing Opioid
Prescribing
"Primum non nocere"
Disclosures
Objectives
Be able to articulate to a patient the reasons why
you are
NOT
going to prescribe opioids
List the four main standards of care when
judiciously
prescribing opioids
Be able to articulate why it is
time to taper off
opioids
Overview
Why
this occurred
Avoiding Opiates
Four
Standards of Care
Time to
Reassess
How did this start?
"only four cases
of reasonably
well documented
addiction"
NEJM 1980 302:123
"We conclude that opioid maintenance therapy can be a safe, salutary and more
humane alternative to
the options of surgery or no treatment in those patients with
intractable non-malignant pain and
no history of drug abuse."
Pain 25 (1986) 171-186
Joint Commission Pain Standard PC.01.02.07
Rational:
The identification and treatment of pain is an important
component of the plan if care. Patients can expect
that their health care providers will ask
them about whether they have pain. When
pain is identified the individual is assessed based on his or her
clinical presentation and in accordance with the care, treatment,
and services provided by the organization.
Pain is NOT the "5
th
Vital Sign"
The "5
th
Vital Sign"
Lanser P, Gesell S. Pain management: the fifth vital sign.
Healthc Benchmarks 2001;8:68-70, 62.
JACHO Guide
2001
"Some clinicians have
inaccurate
and
exaggerated
concerns"
about addiction, tolerance and risk of death."
"This attitude prevails despite the fact
there is no
evidence that addiction is a significant issue
when
persons are given opioids for pain control."
The Joint Commission published a guide sponsored by
Purdue Pharma.
www.rwjf.org/en/grants/grant-records/1997/07/supporting-quality-
improvement-and-jcaho-standard-setting-for-pa.html
http://money.cnn.com/2007/05/10/news/companies/oxycontin/index.htm?cnn=yes
Federation of State Medical Boards
"No
disciplinary action will be taken
against a
practitioner based solely on the quantity and/or
frequency of opioids prescribed."
www.fsmb.org/pdf/2004_grpol_Controlled_Substances.pdf. Accessed April 17, 2013
https://www.statnews.com/2016/06/27/opioid-addiction-
orrin-hatch-ron-wyden/?s_campaign=stat:rss
What is the largest source of Rx opiates for
non-medical use?
a)
Prescribed
by > 1
physician
b)
Bought
from a
drug dealer/stranger
c)
Given
by
friend/relative
d)
Bought
from a
friend/relative
e)
Stolen
from a
friend/relative
Where is the largest source of Rx opiates for
non-medical use?
a)
Prescribed
by > 1
physician
b)
Bought
from a
drug dealer/stranger
c)
Given
by
friend/relative
d)
Bought
from a
friend/relative
e)
Stolen
from a
friend/relative
Sources of opioids for non-medical purposes
70%
20%
10%
Friend or
Relative
Prescribed
Jones CM, Paulozzi LJ, Mack KA. Sources of Prescription Opioid Pain Relievers by Frequency of Past-Year
Nonmedical Use: United States, 2008-2011. JAMA Intern Med. 2014
Other
Who Rx the most opioids in MI ?
A.Surgery
B.Pain management
C.ER/UC
D.Primary care
E.Oncology
Who Rx the most opioids in MI ?
A.Surgery (9%)
B.Pain management (10%)
C.ER/UC (5%)
D.Primary care (64%)
E.Oncology (1%)
"This is why I'm not going
to prescribe narcotics . . ."
Which of the following is not associated
with opioids?
A.
Opioid induced hyperalgesia
B.
Hypothalamic hypogonadism
C.
Physical dependence
D.
Disturbed sleep architecture
E.
Improved pain control with higher doses
Which of the following is not associated
with opioids?
A.
Opioid induced hyperalgesia
B.
Hypothalamic hypogonadism
C.
Physical dependence
D.
Disturbed sleep architecture
E.
Improved pain control with higher doses
Opioid Induced Hyperalgesia
Paradoxical increase
in pain
Diffuse allodynia
unrelated to the original pain
source
Increasing pain
with
increasing dosage
Lee, Marion et al. (2011) "A Comprehensive Review of
Opioid-Induced Hyperalgesia." Pain Physician, 14:145-161
Hypothalamic hypogonadism
Low testosterone and estrogen.
Osteoporosis
57% long acting and 35% short acting
American Society of Interventional Pain Physicians (ASIPP)
guidelines for responsible opioid prescribing in chronic non-cancer
pain: Part 2-guidance. Pain Physician. 2012 July;15:S67-116.
Disturbed Sleep Architecture
Opioids decrease total sleep time, sleep efficiency,
delta sleep, REM sleep and increase time spent in
light sleep.
1
Benyamin R, Trescot AM, Datta S, et al.
Opioid complications and side effects.
Pain Phys 2008;11:S105-S120
Tolerance
A condition in which
higher doses
of
a drug are
required
to produce the
same effect
as during initial use.
Physical Dependence
An
adaptive
physiological state that
occurs with
regular
drug
use
and
results in a
withdrawal syndrome
when drug use is stopped.
Withdrawal: 4-24 hours
"Flu-like and leaky"
.
Fever/Sweating
.
Rhinorrhea
.
Muscle cramps
.
N/V/D/Abd cramping
.
Insomnia
.
Mydriasis
.
Piloerection
Addiction
Compulsive
use
of a drug and
overwhelming
involvement
with its
procurement
and use.
~80% heroin users started
with prescription opioids
Jones CM. Heroin use and heroin use risk
behaviors among nonmedical users of
prescription opioid pain relievers - United
States, 2002-2004 and 2008-2010. Drug
Alcohol Depend. 2013;132(1-2):95-100.
What's the difference?
Morphine
Heroin
6-MAM
Heroin
Hydrocodone
Oxycodone
Morphine
Safer Alternatives
CDC Guideline for Prescribing Opioids
for Chronic Pain -
2016
1. Use behavioral and physical therapies before
medication, particularly opioids.
https://stacks.cdc.gov/view/cdc/38440(Accessed 10-2016)
Safer Alternatives
Heat and cold treatments
Exercise (Home Exercise Program), Handouts
Yoga
Physical and occupational therapy
Safer Alternatives
Emotional and psychological support
Mindfulness training
Acupuncture
OMM
World Health Organization
Analgesic Ladder
Acetaminophen or NSAIDs
Short-acting opioid PRN ±
non-opioid around the clock ±
adjuvant agent
Sustained release opioid or continuous infusion +
short-acting opioid PRN ±
non-opioid ±
adjuvant agent
Safer Alternatives
Non-opioid medication
Compounded agents
Lidocaine patches
Gabapentin
Pregabalin
Duloxetine
Which of the following is the most important
step(s) to take before prescribing opioids?
A. Risk assessment
B. MAPS
C. Urine Drug Screen
D. Pain Management Agreement
E. All the above
Which of the following is the most important
step(s) to take before prescribing opioids?
A. Risk assessment
B. MAPS
C. Urine Drug Screen
D. Pain Management Agreement
E.
All the above
Standard of Care
Risk assessment
MAPS
Urine Drug Screen (UDS)
Pain Management Agreement
Standard of Care
Risk assessment
MAPS
Urine Drug Screen (UDS)
Pain Management Agreement
Opioid Risk Tool (ORT)
1. Age: 16-45
2. Hx Substance Abuse
Alcohol
Illegal Drugs
Prescription Drugs
3. Family Hx Substance Abuse
Alcohol
Illegal Drugs
Prescription Drugs
4. Mental Illness
ADD/OCD/Bipolar/Schizophrenia
Depression - separate scoring
5. Hx Preadolescent Sexual Abuse
Opioid Risk Tool (ORT)
opioidrisk.com
Low Risk 0-3
Moderate Risk 4-7
High Risk ≥ 8
Opioid Risk Tool (ORT)
Standard of Care
Risk assessment
MAPS
Urine Drug Screen (UDS)
Pain Management Agreement
Who Rx the highest doses (MME) in MI?
A.Surgery
B.Pain management
C.ER/UC
D.Primary care
E.Oncology
Who Rx the highest doses (MME) in MI?
A.Surgery
B.Pain management
C.ER/UC
D.Primary care
E.Oncology
Primary care is the 1
st
largest Rx of
lorazepam.
Who is the 2
nd
?
A.Surgery
B.Pain management
C.Psychiatry
D.Primary care
E.Oncology
Primary care is the 1
st
largest Rx of
lorazepam.
Who is the 2
nd
?
A.Surgery
B.Pain management
C.Psychiatry
D.Primary care
E.Oncology
Doctor Shopping and Overdose Death: 2009-2012
< 25 Deaths
1.4-2.3/100
3
2.4-3.1
3.2-4.1
4.6-6.0
A Profile of Drug Overdose Deaths Using the Michigan
Automated Prescription System (MAPS)
Office of Recovery Oriented Systems of Care Staff: Su Min Oh
Standard of Care
Risk assessment
MAPS
Urine Drug Screen (UDS)
Pain Management Agreement
Drug Testing
Detect
non-prescribed
drugs
Detect the
absence
of drugs
Point Of Care testing (in office)
High rates of false +/-
No toxicologist to consult
Standard of Care
Risk assessment
MAPS
Urine Drug Screen (UDS)
Pain Management Agreement
But, wait, there's more . . .
Store SECURELY
Encourage those on opioids to: Store
SECURELY
"Is there a more secure area to keep your pills
besides your":
Drawer at work
Purse
Glove box
Medicine Cabinet
Dispose PROPERLY
Dispose PROPERLY
Do you really need to save them "just in
case"?
Give them a list of disposal sites
How to Dispose of Unused
Medicines
Take drugs out of their
original containers and
mix them with an
undesirable substance,
such as used coffee
grounds ...
www.fda.gov/downloads/Drugs/ResourcesForYou/Consumers/BuyingUsing
MedicineSafely/UnderstandingOver-the-CounterMedicines/ucm107163.pdf
(Accessed 5-2015)
Never SHARE
Encourage those on opioids to: Never SHARE
Felony
Don't want to create any more addictions
What are you going to change?
Three
classes
Patients not on opioids
work hard
provide more effective and safer options
Patients on opioids
reassess
frequently
Opioid addiction
Families Against Narcotics
https://www.npr.org/sections/health-
shots/2016/01/11/462390288/anatomy-of-
addiction-how-heroin-and-opioids-hijack-the-brain
Transitioning Off
Opioids
"Plant the seed!"
First Do No Harm!
"Primum non nocere"
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